You can do:
lxc config device override <instance> <device> hwaddr 00:50:56:01:32:22
The override
command copies the NIC config from the profile into the instance and then modifies the config key(s) you provide.
You can do:
lxc config device override <instance> <device> hwaddr 00:50:56:01:32:22
The override
command copies the NIC config from the profile into the instance and then modifies the config key(s) you provide.